“NEONATAL BULLOUS CUTANEOUS MASTOCYTOSIS: A RARE AND STRIKING PRESENTATION IN EARLY INFANCY"

Abstract

Cutaneous mastocytosis is a rare disorder characterised by abnormal proliferation and accumulation of mast cells in the skin. It is most frequently seen in infancy and childhood, with varied morphological presentations ranging from macules and papules to plaques and bullous lesions. We report the case of a 31-day-old male infant presenting with a polymorphic cutaneous eruption noted since the tenth day of life. The lesions initially appeared as tense bullae which subsequently evolved into indurated plaques and maculopapular lesions. There was no history of fever, pruritus, flushing, or systemic symptoms. Clinical examination revealed multiple discrete and confluent hyperpigmented macules, papules, and indurated plaques distributed over the trunk and extremities, along with residual post-bullous hyperpigmentation. Systemic examination was unremarkable. The constellation of early-onset, polymorphic morphology and absence of systemic involvement favoured a diagnosis of cutaneous mastocytosis. Early identification and parental counselling are crucial in preventing disease exacerbation and guiding follow-up.