BALANCING AUTOIMMUNITY AND INFECTION: COEXISTENCE OF ILEOCAECAL TUBERCULOSIS AND SJÖGREN’S SYNDROME – A CASE REPORT AND REVIEW OF LITERATURE

Authors

  • DR. ANUSUYA C POSTGRADUATE, DEPARTMENT OF GENERAL SURGERY, SAVEETHA MEDICAL COLLEGE AND HOSPITAL, THANDALAM, TAMIL NADU, INDIA
  • PROF. DR. KHALILUR RAHMAN PROFESSOR, DEPARTMENT OF GENERAL SURGERY, SAVEETHA MEDICAL COLLEGE AND HOSPITAL, THANDALAM, TAMIL NADU, INDIA
  • DR. RAHUL RAJ ASSOCIATE PROFESSOR, DEPARTMENT OF GENERAL SURGERY, SAVEETHA MEDICAL COLLEGE AND HOSPITAL, THANDALAM, TAMIL NADU, INDIA
  • DR. DAKSHAY CHORDIA SENIOR RESIDENT, DEPARTMENT OF GENERAL SURGERY, SAVEETHA MEDICAL COLLEGE AND HOSPITAL, THANDALAM, TAMIL NADU, INDIA
  • DR.V. RAMYA PROFESSOR, DEPARTMENT OF PERIODONTOLOGY, SREE BALAJI DENTAL COLLEGE & HOSPITAL, CHENNAI, INDIA

Keywords:

Sjögren’s syndrome; Ileocaecal tuberculosis; Autoimmune disease; Immunosuppression; Multidisciplinary care

Abstract

Background: The coexistence of autoimmune disorders such as Sjögren’s syndrome (SS) and infectious diseases like tuberculosis (TB) poses significant diagnostic and therapeutic challenges, especially in TB-endemic regions. Immunosuppressive therapy for SS increases TB reactivation risk, complicating management strategies.

Case Presentation: A 45-year-old female with SS presented with progressive lower abdominal pain. Imaging suggested appendicular inflammation; however, laparoscopy revealed an ileocaecal mass. Limited resection of the terminal ileum and proximal ascending colon was performed. Histopathology confirmed ileocaecal TB. The patient received anti-tubercular therapy alongside adjusted immunosuppressive treatment under multidisciplinary care.

Conclusion: This case underscores the importance of comprehensive screening for latent TB before immunosuppressive therapy, individualized perioperative immuno suppressive management, and multidisciplinary coordination in patients with overlapping autoimmune and infectious diseases.

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How to Cite

C, D. A., RAHMAN, P. D. K., RAJ, D. R., CHORDIA, D. D., & RAMYA, D. (2025). BALANCING AUTOIMMUNITY AND INFECTION: COEXISTENCE OF ILEOCAECAL TUBERCULOSIS AND SJÖGREN’S SYNDROME – A CASE REPORT AND REVIEW OF LITERATURE. TPM – Testing, Psychometrics, Methodology in Applied Psychology, 32(S3(2025) : Posted 07 July), 1431–1436. Retrieved from https://tpmap.org/submission/index.php/tpm/article/view/844

Issue

Vol. 32 No. S3(2025) : Posted 07 July (2025)

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Articles

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