MULTIPLE HEREDITARY EXOSTOSIS PRESENTING WITH CHONDRO-SARCOMATOUS TRANSFORMATION WITH PARAPARESIS: A CASE REPORT

Abstract

Chondrosarcoma arising from hereditary multiple exostoses(HME) which is a rare but serious complication that warrants close attention due to its significant impact on patient health. This is a case report of a 54year old male who had been diagnosed with HME, had subsequently developed chondrosarcoma in his lumbar spine. This malignant transformation led to paraparesis, a condition characterized by partial paralysis of the lower limbs. In this manuscript, we delve into the clinical presentation of this patient, outlining the initial symptoms and progression of the disease. The diagnostic workup is detailed, including imaging studies and histopathological examination, which confirmed the presence of chondrosarcoma. Treatment strategies are thoroughly discussed, highlighting surgical interventions, possible adjuvant therapies, and the rationale behind the chosen management approach. The outcomes are also examined, providing insights into the prognosis and recovery process. Emphasis is placed on the challenges faced in managing such complex cases and the principles guiding effective treatment.