ANAESTHETIC MANAGEMENT FOR FULL MOUTH REHABILITATION IN A CHILD WITH MULTIPLE CARBOXYLASE ENZYME DEFICIENCY

Abstract

MCD Multiple carboxylase deficiency, is a rare autosomal recessive metabolic disorder, that results in impaired biotin-dependent enzyme activity, causing extensive metabolic, neuromuscular and respiratory abnormalities that can be fatal during anesthesia. Here we discuss the clinical and anaesthetic management of a 9 year old child with MCD, the relevant Preoperative investigations and preparations done including metabolic optimisation and systemic optimisation. In this case general Anaesthesia with intravenous induction and maintenance with volatile anaesthetics and non-depolarizing muscle relaxant ensured stable intraoperative conditions. Close monitoring of metabolic parameters and meticulous postoperative care facilitated a smooth recovery, highlighting the importance of tailored anaesthesia in managing paediatric patients with complex metabolic disorders.