A STUDY DETERMINING THE ASSOCIATION OF HELICOBACTER PYLORI AND CHOLELITHIASIS

Abstract

Cholelithiasis, characterized by the formation of gallstones within the gallbladder or bile ducts, is a common gastrointestinal disorder affecting millions worldwide. Although the connection among the  H. pylori and gallstones have been studied before, no conclusion has been reached. Additionally, in the patients gallbladder mucosa along with gallstones has been found by H.pylori. Patients whose diagnosis of cholelithiasis was confirmed by imaging methods were included in our study. Endoscopy was performed in patients diagnosed with cholelithiasis and histopathological data of gastric mucosa biopsies were followed. In the research, the connection between cholelithiasis and Helicobacter pylori  was investigated. Most patients (26%) were aged between 20-29 years with a minority (2%) being less than 20 years old. Among the total population, biopsy-proven positive for 11 (22%) people by H. pylori infection. When it was difference in gallstone diagnosis is compared between the positive and  negative group of H-pylori, the significance with p value indicates the difference. Our results show in a small number of patients that cholelithiasis have been linked with H.pylori. However, the research could not accept the results. Future research is  recommended to do mechanism of H pylori infection associated with gallbladder disease such as cholelithiasis.