ASSESSING THE CORRELATION OF THYROID DYSFUNCTION IN PATIENT WITH ABNORMAL UTERINE BLEEDING IN SKBZ/CMH RAWALKOT

Abstract

Objective To determine the frequency of thyroid dysfunction in females presenting with Abnormal Uterine Bleeding (AUB) and to assess its correlation with various demographic and clinical factors at a tertiary care hospital in the Rawalkot region.

Methodology This was a cross-sectional study conducted at Obstetrics and Gynaecology Department of CMH Rawalakot from July 2025 to October 2025. A total of 200 non-pregnant females aged 18-45 years, presenting with AUB according to the operational definition (irregular, excessive, or frequent uterine bleeding), were selected using non-probability consecutive sampling. Thyroid dysfunction was defined as a serum TSH>5 IU/L. Data were analyzed using SPSS v.22, and the Chi-square test was applied for stratified analysis to control for potential effect modifiers.

Results The overall frequency of thyroid dysfunction was found in 16.0(n=32) of AUB patients. Stratification revealed statistically significant correlations between thyroid dysfunction and age (P=0.001), BMI ≥ 25 kg/m2 (P=0.02), anemia (P=0.04), and a family history of thyroid dysfunction (P=0.005). The prevalence was highest in the 36-45 year age group (28.3%) and among patients with a positive family history (33.3%).

Conclusion The frequency of thyroid dysfunction in females with Abnormal Uterine Bleeding in the local population is substantial (16.0%). Given the significant associations with AUB and the readily treatable nature of thyroid dysfunction, routine screening using thyroid function tests should be implemented for all females presenting with Abnormal Uterine Bleeding in this setting.