COMPARISON OF INTRAPERITONEAL IRRIGATION PLUS PERIPORTAL INFILTRATION USING BUPIVACAINE VERSUS NO BUPIVACAINE AFTER LAPAROSCOPIC CHOLECYSTECTOMY

Abstract

Objective: To compare the outcome of intraperitoneal irrigation plus periportal infiltration using bupivacaine versus no bupivacaine after laparoscopic cholecystectomy Study Design: Randomized controlled trial Place and Duration of Study: Surgical Unit-2, Sahiwal Teaching Hospital, Sahiwal from April 2025 to October 2025.
Methodology: A total of 60 patients, consisting of 30 patients in each group, meeting the inclusion criteria, were selected for this study from the operation theater of Sahiwal Teaching Hospital, Sahiwal and underwent laparoscopic cholecystectomy in 6 months (from April 2025 to October 2025). The patients were randomly selected and divided into two groups using the lottery system. Group A patients did not receive any bupivacaine while Group B patients received 40ml of intraperitoneal 0.25% bupivacaine injection and additional 20ml of 0.25% bupivacaine at all four port sites (5ml at each site). Results: Overall, patients who had bupivacaine (Group B) had significantly better postoperative pain management and needed less rescue analgesic administration than patients who did not receive bupivacaine (Group A). Also, patients who had bupivacaine (Group B) had lower mean scores of pain at most times following surgery. The cumulative dose of rescue analgesic medications over 24 hours was appreciably lower in Group B. Fewer patients in Group B needed rescue analgesic administration at 1, 6, and 12 hours following surgery.
Conclusion: Generally, bupivacaine was found to be of great use in supplementing postoperative pain management, ensuring a reduction in postoperative analgesic use.