PHARMACOECONOMICS OF ORAL WEIGHT-LOWERING DRUGS IN TYPE 2 DIABETES: A COMPARATIVE STUDY OF SGLT-2 INHIBITORS AND GLP-1 ANALOGUES IN INDIA

Authors

  • SULTHAN AL RASHID DEPARTMENT OF PHARMACOLOGY, SAVEETHA MEDICAL COLLEGE AND HOSPITALS, SAVEETHA INSTITUTE OF MEDICAL AND TECHNICAL SCIENCES, SAVEETHA UNIVERSITY, CHENNAI–602105, INDIA;
  • PREETHA SELVA DEPARTMENT OF PHARMACOLOGY, SAVEETHA MEDICAL COLLEGE AND HOSPITALS, SAVEETHA INSTITUTE OF MEDICAL AND TECHNICAL SCIENCES, SAVEETHA UNIVERSITY, CHENNAI–602105, INDIA;
  • V R YASHVANTHAN DEPARTMENT OF PHARMACOLOGY, SAVEETHA MEDICAL COLLEGE AND HOSPITALS, SAVEETHA INSTITUTE OF MEDICAL AND TECHNICAL SCIENCES, SAVEETHA UNIVERSITY, CHENNAI–602105, INDIA;

Keywords:

Cost-effective, GLP-1 analogues,Pharmacoeconomics, SGLT-2 inhibitors, Type 2 diabetes, Weight-lowering drugs.

Abstract

Objective:To assess the affordability and adherence implications of SGLT-2 inhibitors and GLP-1 analogues in the Indian context, with a focus on Pharmacoeconomics and cost variations

Methods:Medication price data were collected from the Current Index of Medical Specialties (CIMS) and accredited online sources for SGLT-2 inhibitors and GLP-1 analogues from January 2024 to April 2024. Percentage cost variation was calculated to analyse price differences among brands.

Results: SGLT-2 inhibitors, particularly dapagliflozin, exhibited significant price variations, with costs ranging from INR 5.9 to INR 30 per tablet. Combination therapies showed moderate variations, while GLP-1 analogues, including oral semaglutide, were substantially more expensive, ranging from INR 294.81 to INR 387 per tablet.

Conclusion: The study underscores the need for cost-effective prescribing practices to improve affordability and adherence, particularly for resource-constrained settings in India. Integration of these drugs into essential medicine lists and price regulation could alleviate financial strain and enhance accessibility.

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How to Cite

RASHID, S. A., SELVA, P., & YASHVANTHAN, V. R. (2025). PHARMACOECONOMICS OF ORAL WEIGHT-LOWERING DRUGS IN TYPE 2 DIABETES: A COMPARATIVE STUDY OF SGLT-2 INHIBITORS AND GLP-1 ANALOGUES IN INDIA. TPM – Testing, Psychometrics, Methodology in Applied Psychology, 32(S2(2025) : Posted 09 June), 792–800. Retrieved from https://tpmap.org/submission/index.php/tpm/article/view/299

Issue

Vol. 32 No. S2(2025) : Posted 09 June (2025)

Section

Articles

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