MARINE-DERIVED COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASES

Abstract

Their significance is highlighted by the chronicity, expense, and complexity of autoimmune diseases (Ads), which impact many organs and tissues.   Addressing ads in patient populations calls for a more thorough strategy.   An innovative method of obtaining an integrated therapeutic agent is through natural phytoconstituents.  The marine environment is rich in a wide range of biomolecules with advantageous properties.  Numerous substances that have been demonstrated to have immunomodulatory properties and may have therapeutic uses for Ads have been discovered in sponges, bacteria, fungi, cyanobacteria, and algae.  It has been demonstrated that bioactive marine chemicals influence immunological processes and are essential for immunotherapies. The information regarding the particular effects of chemicals derived from marine organisms being used as food supplements or in the management of immune system diseases is increasing. In this paper, numerous sources of possible marine metabolic compounds like seagoing plants and animals are discussed. Following their isolation, characterization, and identification in recent years, a number of marine phytoconstituents are currently undergoing investigations for potential human use.  In this review, we have attempted to compile data on phytoconstituents of marine origin that exhibit immunomodulatory and anti-inflammatory properties, and we have briefly examined their modes of action.