THE ROLE OF MARINE COMPOUNDS IN IMMUNOMODULATION

Abstract

Marine animals have a wealth of biologically active compounds that can be used to cure and prevent a variety of illnesses, including cancer, inflammation, immune system problems, and others.   One advantage of studying marine life is that it can show a vast array of biodiversity and the chemical diversity of marine natural products.  Numerous investigations have concentrated on marine substances that may have pharmacological uses, such as immunomodulators, for the treatment of immune-mediated illnesses and cancer.Immune system modulation is any change in the immune response that could result in the induction, expression, amplification, or inhibition of any immune response phase.   Studies frequently focus on the impact of chemicals produced from marine sources on macrophages and lymphocytes by monitoring the release of mediators (cytokines) using the immunological technique enzyme-linked immunosorbent assay (ELISA), Western blot, immunofluorescence, and real-time PCR.  The main sources are fish, mollusks, sponges, bacteria, microalgae, macroalgae, and corals.  The compounds originating from marine sources that have been discovered as possible immunomodulatory medications within the past three years are the main topic of this review.