MARINE-INSPIRED DRUG DESIGN: A NEW APPROACH TO PHARMACEUTICAL DEVELOPMENT

Abstract

Cone snails, cyanobacteria, fungi, bacteria, and halophytes are just a few of the marine creatures that have produced the bioactive chemicals needed for therapeutic development. More than 90% of oceanic biomass comes from these sources, which have exceptional chemical qualities and a wealth of potential applications, especially in the treatment of cancer. The review emphasizes how marine natural materials' unique chemical structures and bioactivity have historically led to successful medication discovery.It clarifies the elements that led to these findings, including sophisticated isolation and characterisation methods, knowledge of marine ecological niches, and multidisciplinary study by marine biologists, chemists, and pharmacologists.  The difficulty of chemical synthesis, restricted distribution, and environmental considerations all cause constraints.  Preclinical research, clinical testing, and extensive testing are necessary to turn medications originating from marine sources into effective medicines.  Future scientific and technological developments like metagenomics and synthetic biology present excellent opportunities for better discovery and quicker development of medications derived from marine sources.There is a lot of room for the development of new drugs, and continued research into marine natural products could greatly enhance medical knowledge while accounting for sustainability and environmental effects.