A NEW SCALE CPECT SCALE FOR ASSESSING QUALITY OF LIFE IN PEOPLE WITH SPECTRUM OF NASAL DISEASES

Abstract

Introduction: Nasal diseases, such as chronic rhinosinusitis, allergic rhinitis, and related sinonasal disorders, significantly affect patients' quality of life (QoL), causing persistent symptoms that interfere with daily functioning. Existing tools like the Sinonasal Outcome Test (SNOT-22) are valuable but lack comprehensive assessments that integrate clinical and objective data. The Comprehensive Patient Evaluation of Chronic Transnasal Symptoms (CPECT) scale was developed to address these limitations and provide a multidimensional assessment framework.

Materials and Methods: This randomized controlled study included 100 participants (mean age 38 ± 10 years) with a range of nasal conditions. The CPECT scale was developed using expert input and statistical validation methods, including exploratory factor analysis. Data were collected via questionnaires, clinical examinations, endoscopy, and CT imaging. Reliability was assessed using Cronbach's alpha, while ANOVA and correlation analyses evaluated the scale's validity and interdependence of components.

Results: The overall mean CPECT score was 18.6 ± 5.2. Subscale mean scores were 7.5 ± 2.3 for Clinical Picture (CP), 6.1 ± 1.8 for Endoscopy (E), and 5.0 ± 2.1 for CT findings. Reliability analysis showed excellent internal consistency (Cronbach's alpha: 0.89). ANOVA revealed significant differences in scores across nasal conditions (p < 0.001). Correlation analysis demonstrated strong relationships between CP and patient-reported QoL (r = 0.72, p < 0.001) and high interdependence between endoscopy and CP (r = 0.79, p < 0.001).

Conclusion: The CPECT scale is a reliable, multidimensional tool for assessing QoL in nasal diseases. It integrates subjective and objective data, providing a comprehensive framework for clinical and research applications. Future studies should explore its responsiveness to therapeutic interventions and its utility in diverse populations.